About us

Apmonia Therapeutics was founded in 2019 as spin-off of CNRS and Reims university (UMR 7369 MEDyC). Executive team now gathers together members with decades of experience in leading research institutes and biotech industry.

Team in place

Message from the President

We have embarked on an ambitious adventure to develop groundbreaking therapeutic agents targeting the extracellular matrix. We make our best effort every day to fulfill the legitimate expectations of our partners, with the social commitment to improve the lives of patients suffering from life-threatening diseases around the globe.

Whether you are a potential corporate partner, a scientific researcher or someone looking for an exciting career, we appreciate very much your interest in Apmonia Therapeutics, and will welcome your encouragement to make it a leader in the future of biotech industry.

Albin JEANNE
President

PhD

Dr. JEANNE completed his PhD in biochemistry and cell biology within CNRS 7369 MEDyC research unit. He has authored 13 peer-reviewed scientific publications on TSP-1 pathobiology and won numerous international awards. During past professional experience as a project manager, he developed his expertise in translational drug development while building capacity to manage research programs, partnerships, and reach deliverables. As a co-inventor of TAX2 patents, he engineered the first ever antagonists being selective for TSP- 1/CD47 interaction. Beyond scientific background, Albin JEANNE acquired strong management skills and strategic insights as he completed the Challenge+ program at HEC international business school.

Supervisory Board

Abderrahim LACHGAR
PhD

Dr. LACHGAR has a strong background of over 20 years in biopharmaceutical industry, mainly in immunotherapy. Further to his PhD in immunology, he contributed to the initiation, management and development of different biotech companies. He was involved, as top-manager, in various national and international drug developments and clinical trials. In addition to his scientific and management expertise, he acquired a strong background in science and technology assessment and forecasting. Concomitantly, Abderrahim was actively involved in different international scientific collaboration as advisors at the Academy of Sciences as well as at different government agencies and organizations. He was involved in the French research agency programs design (ANR-2030) as member of the prospective team and in Medicen Cluster as Board member and member of the translational research steering committee.

Damien SALAUZE

PhD, PharmD, MBA

Dr. SALAUZE, PhD, MBA, has extensive experience as a pharmaceutical and biotechnology industry executive and venture capital investor in life science companies. He currently serves as Head of FINDMED, a technology transfer program financed by the French government. Dr. Salauze previously held positions at Aventis as Head of a Toxicology Department, then Senior International Marketing Director (Oncology). He has also been a partner at Auriga Ventures, as well as the CEO of Novagali Pharma and Sepal Pharma. Until 2016, Damien served as Tech Transfer Officer at the Institut Curie in Paris.

Georges RAWADI
PhD, MSc

A former researcher at the Institut Pasteur, Georges RAWADI was Vice-President of Business Development & Intellectual Property and a member of the management team at Celyad.

He previously served in various business development roles at Cellectis, Galapagos, ProStrakan and Sanofi-Aventis and led strategic alliance development consulting assignments.

He holds a PhD in Microbiology from Pierre and Marie Curie University (France) and a master’s degree in Management and Strategy in the Health Industry from ESSEC Business School.

Scientific & Clinical Advisory Board

Stéphane DEDIEU
Chair
PhD
CNRS, Reims University

Professor Stéphane DEDIEU holds a PhD from the University of Bordeaux where he was trained in biochemistry and molecular biology during the early 2000s. He currently leads a 40 people research team within a multidisciplinary CNRS labelled unit (UMR CNRS 7369 MEDyC) affiliated to the University of Reims. He has expertise in cancer biology and therapeutic targeting of matricellular receptors. Prof DEDIEU carries out numerous missions of scientific advice and expertise. In particular, he has been a member of the National Committee for Scientific Research since 2012 (commission dedicated to pharmacology, health engineering and technologies) and member of the board since 2016. He is a member of the Scientific and Clinical Committee of Canceropole-Est and has served on the Interregional Scientific Council of the League Against Cancer for the past four years. Prof DEDIEU is co-founder of Apmonia Therapoutics and co-inventor of the patents exploited by the company.

Olivier ADOTEVI
MD, PhD
Besançon Hospital

Professor Olivier ADOTEVI completed his PhD training in immuno-oncology at 2006 at the Pierre & Marie Curie University (Paris) and continued with a post-doctorate at Pasteur Institute Paris. To date, he is Professor of Clinical Immunology and thoracic oncology at the Regional Institute of Cancer, CHU de Besançon. He is the head of the INSERM research team "Molecular cancer immunotherapy, TIM-C" UMR1098 in Besançon since 2016. Pr. Adotévi and his team are leading a research program dedicated to the identification of tumor antigens involved, the initiation and regulation of CD4 T lymphocytes, in the development of anticancer immunotherapy (vaccine, CAR-T cell...) as well as the identification of immune biomarkers. In the few last years, its team initiated innovative anticancer vaccine program in clinic. This CD4 Th1-inducer vaccine called UCPVax is currently evaluated in several cancers as monotherapy or in combination with immune checkpoint inhibitors.

He previously served in various business development roles at Cellectis, Galapagos, ProStrakan and Sanofi-Aventis and led strategic alliance development consulting assignments.

He holds a PhD in Microbiology from Pierre and Marie Curie University (France) and a master’s degree in Management and Strategy in the Health Industry from ESSEC Business School.

Alexandra LEARY
MD, PhD
Gustave Roussy Institute

Alexandra LEARY, MD, PhD is a medical oncologist and translational researcher specializing in gynecological tumors at Gustave Roussy. In 2011, she joined the Gustave Roussy Cancer Center as a medical oncologist treating ovarian, endometrial and cervical cancers with a special focus on early phase drug development. She is also team leader for gynecological oncology translational research within the laboratory of Predictive Biomarkers and Novel Targeted Therapeutics (INSERM U981) at Gustave Roussy. She obtained her medical degree from Georgetown University Medical School in Washington, DC and completed an Internal Medicine Residency at Northwestern University Hospital in Chicago. She then pursued her training in Medical Oncology at the Royal Marsden Hospital in London and obtained a PhD from the Institute of Cancer Research/University of London. Nationally, she sits on the board of the French clinical trial intergroup, GINECO and is President of the GiNEGEPS (GINECO group on Early Phase Studies). Internationally, she is a member of the ENGOT translational research group, French representative at the GCIG (Gynecological Cancers InterGroup) and co-chair the GCIG phase II trial group.

Armand BENSUSSAN
PhD
Saint-Louis Hospital, Jean Godinot Institute

Professor Armand BENSUSSAN completed his PhD training during the early 1980s in the laboratories of Professor Jean DAUSSET (Saint-Louis Hospital, Paris, France) and Professor Stuart F SCHLOSSMAN (Harvard Medical School, DFCI, Boston, MA). He is currently Research director at INSERM and chief of the Skin Research Center and of the INSERM unit 976 at Saint-Louis Hospital in Paris, France. He obtained several awards including two distinct French Academy of Sciences awards, the clinical investigation award from the French foundation for medical research, the immunology Bernard HALPERN award and the national award of projects leaders for the creation and/or the development of highly innovative technology companies. He was the past president of the French society of immunology. He is author of more than 340 international scientific publications, editor of two scientific books and designated as co-inventor in more than 30 patents, which most of them are licensed to industry.

Olivier BOUCHÉ
MD, PhD
Reims Hospital

Olivier BOUCHE, MD, PhD is a hospital practitioner specializing in gastroenterology and digestive oncology. He is affiliated with the Robert Debré Reims Hospital where he is Head of the ambulatory oncology-haematology unit. He is also in charge of the multidisciplinary tumour board meeting of digestive cancerology. He is the coordinator of the steering committee of the National Digestive Cancer Thesaurus and was scientific president of the Fédération Francophone de Cancérologie Digestive between 2010 and 2016. He is also member of the ARCAD (foundation in digestive oncology) and ONCOCHA (regional oncology association) network of which he was vice-president, and scientific honorary member of the French association of GIST (Gastro-Intestinal Stromal Tumour) patients. He has participated for many years in numerous clinical trials and is the author of nearly 300 referenced scientific articles.

Supervisory Board

Scientific & Clinical Advisory Board

Abderrahim LACHGAR
PhD

Dr. LACHGAR has a strong background of over 20 years in biopharmaceutical industry, mainly in immunotherapy. Further to his PhD in immunology, he contributed to the initiation, management and development of different biotech companies. He was involved, as top-manager, in various national and international drug developments and clinical trials. In addition to his scientific and management expertise, he acquired a strong background in science and technology assessment and forecasting. Concomitantly, Abderrahim was actively involved in different international scientific collaboration as advisors at the Academy of Sciences as well as at different government agencies and organizations. He was involved in the French research agency programs design (ANR-2030) as member of the prospective team and in Medicen Cluster as Board member and member of the translational research steering committee.

Stéphane DEDIEU
Chair
PhD
CNRS, Reims University

Professor Stéphane DEDIEU holds a PhD from the University of Bordeaux where he was trained in biochemistry and molecular biology during the early 2000s. He currently leads a 40 people research team within a multidisciplinary CNRS labelled unit (UMR CNRS 7369 MEDyC) affiliated to the University of Reims. He has expertise in cancer biology and therapeutic targeting of matricellular receptors. Prof DEDIEU carries out numerous missions of scientific advice and expertise. In particular, he has been a member of the National Committee for Scientific Research since 2012 (commission dedicated to pharmacology, health engineering and technologies) and member of the board since 2016. He is a member of the Scientific and Clinical Committee of Canceropole-Est and has served on the Interregional Scientific Council of the League Against Cancer for the past four years. Prof DEDIEU is co-founder of Apmonia Therapoutics and co-inventor of the patents exploited by the company.

Damien SALAUZE

PhD, PharmD, MBA

Dr. SALAUZE, PhD, MBA, has extensive experience as a pharmaceutical and biotechnology industry executive and venture capital investor in life science companies. He currently serves as Head of FINDMED, a technology transfer program financed by the French government. Dr. Salauze previously held positions at Aventis as Head of a Toxicology Department, then Senior International Marketing Director (Oncology). He has also been a partner at Auriga Ventures, as well as the CEO of Novagali Pharma and Sepal Pharma. Until 2016, Damien served as Tech Transfer Officer at the Institut Curie in Paris.

Alexandra LEARY
MD, PhD
Gustave Roussy Institute

Alexandra LEARY, MD, PhD is a medical oncologist and translational researcher specializing in gynecological tumors at Gustave Roussy. In 2011, she joined the Gustave Roussy Cancer Center as a medical oncologist treating ovarian, endometrial and cervical cancers with a special focus on early phase drug development. She is also team leader for gynecological oncology translational research within the laboratory of Predictive Biomarkers and Novel Targeted Therapeutics (INSERM U981) at Gustave Roussy. She obtained her medical degree from Georgetown University Medical School in Washington, DC and completed an Internal Medicine Residency at Northwestern University Hospital in Chicago. She then pursued her training in Medical Oncology at the Royal Marsden Hospital in London and obtained a PhD from the Institute of Cancer Research/University of London. Nationally, she sits on the board of the French clinical trial intergroup, GINECO and is President of the GiNEGEPS (GINECO group on Early Phase Studies). Internationally, she is a member of the ENGOT translational research group, French representative at the GCIG (Gynecological Cancers InterGroup) and co-chair the GCIG phase II trial group.

Georges RAWADI
PhD, MSc

A former researcher at the Institut Pasteur, Georges RAWADI was Vice-President of Business Development & Intellectual Property and a member of the management team at Celyad.

He previously served in various business development roles at Cellectis, Galapagos, ProStrakan and Sanofi-Aventis and led strategic alliance development consulting assignments.

He holds a PhD in Microbiology from Pierre and Marie Curie University (France) and a master’s degree in Management and Strategy in the Health Industry from ESSEC Business School.

Olivier ADOTEVI
MD, PhD
Besançon Hospital

Professor Olivier ADOTEVI completed his PhD training in immuno-oncology at 2006 at the Pierre & Marie Curie University (Paris) and continued with a post-doctorate at Pasteur Institute Paris. To date, he is Professor of Clinical Immunology and thoracic oncology at the Regional Institute of Cancer, CHU de Besançon. He is the head of the INSERM research team "Molecular cancer immunotherapy, TIM-C" UMR1098 in Besançon since 2016. Pr. Adotévi and his team are leading a research program dedicated to the identification of tumor antigens involved, the initiation and regulation of CD4 T lymphocytes, in the development of anticancer immunotherapy (vaccine, CAR-T cell...) as well as the identification of immune biomarkers. In the few last years, its team initiated innovative anticancer vaccine program in clinic. This CD4 Th1-inducer vaccine called UCPVax is currently evaluated in several cancers as monotherapy or in combination with immune checkpoint inhibitors.

He previously served in various business development roles at Cellectis, Galapagos, ProStrakan and Sanofi-Aventis and led strategic alliance development consulting assignments.

He holds a PhD in Microbiology from Pierre and Marie Curie University (France) and a master’s degree in Management and Strategy in the Health Industry from ESSEC Business School.

Armand BENSUSSAN
PhD
Saint-Louis Hospital, Jean Godinot Institute

Professor Armand BENSUSSAN completed his PhD training during the early 1980s in the laboratories of Professor Jean DAUSSET (Saint-Louis Hospital, Paris, France) and Professor Stuart F SCHLOSSMAN (Harvard Medical School, DFCI, Boston, MA). He is currently Research director at INSERM and chief of the Skin Research Center and of the INSERM unit 976 at Saint-Louis Hospital in Paris, France. He obtained several awards including two distinct French Academy of Sciences awards, the clinical investigation award from the French foundation for medical research, the immunology Bernard HALPERN award and the national award of projects leaders for the creation and/or the development of highly innovative technology companies. He was the past president of the French society of immunology. He is author of more than 340 international scientific publications, editor of two scientific books and designated as co-inventor in more than 30 patents, which most of them are licensed to industry.

Olivier BOUCHÉ
MD, PhD
Reims Hospital

Olivier BOUCHE, MD, PhD is a hospital practitioner specializing in gastroenterology and digestive oncology. He is affiliated with the Robert Debré Reims Hospital where he is Head of the ambulatory oncology-haematology unit. He is also in charge of the multidisciplinary tumour board meeting of digestive cancerology. He is the coordinator of the steering committee of the National Digestive Cancer Thesaurus and was scientific president of the Fédération Francophone de Cancérologie Digestive between 2010 and 2016. He is also member of the ARCAD (foundation in digestive oncology) and ONCOCHA (regional oncology association) network of which he was vice-president, and scientific honorary member of the French association of GIST (Gastro-Intestinal Stromal Tumour) patients. He has participated for many years in numerous clinical trials and is the author of nearly 300 referenced scientific articles.