Targetingextracellular matrixsignaling in cancer

Based in France and Belgium, Apmonia Therapeutics develops first-in-class peptides to modulate the tumor microenvironment.

Explore our pipeline
Clinical-stage peptide therapeuticsLead program TAX2 (AP-01): Phase 1/2a ongoing in advanced solid tumors.

TAX2, our lead program

PHASE 1/2a ONGOING

TAX2 (AP-01) is a first-in-class cyclic peptide that binds TSP-1 to selectively disrupt its interaction with CD47, with the aim of restoring anti-tumor immunity.

Its development is supported by a comprehensive nonclinical package and independent preclinical findings published in Nature Immunology.

Beyond TAX2, our pipeline includes preclinical programs in oncology and other areas.

Explore our pipeline
3D model of TAX2, a cyclic peptide candidate
First-in-class cyclic peptideTSP-1/CD47 antagonistPhase 1/2a ongoingAdvanced solid tumors

Extracellular matrix targeting technology

We develop peptides to modulate interactions between extracellular proteins and cell-surface receptors, opening new therapeutic approaches in oncology.

Discover the technology
Scientist working at a laboratory instrument

Designing peptides for challenging extracellular targets

Our proprietary platform integrates computational design with peptide engineering and experimental validation.

Computational design

We characterize challenging extracellular targets using AI-assisted molecular modeling and molecular dynamics simulations.

Peptide engineering and validation

We engineer and test peptide candidates to optimize biological activity, stability and manufacturability.

The expertise to advance peptide therapeutics

Our team brings together expertise in extracellular biology, peptide discovery, nonclinical development, manufacturing and clinical development.

Our programs are supported by scientific, clinical and strategic advisors.

Meet our team
Co-founders
Albin Jeanne, Abderrahim Lachgar and Stéphane Dedieu, co-founders of Apmonia Therapeutics
  • Albin JEANNECEO / CSO
  • Abderrahim LACHGARBoard Member
  • Stéphane DEDIEUChair of the Scientific and Clinical Advisory Board

Latest news

Stay informed about our scientific advances, clinical progress, and company updates.

News